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Ion. Proc Natl Acad Sci U S A 2006, 103:18727?8732. Wang R, Zhang

por Kaylene Snowball (23-09-2020)

Ion. Proc Natl Acad Sci U S A 2006, 103:18727?8732. Wang R, Zhang YW, Zhang X, Liu R, Zhang X, Hong S, Xia K, Xia J, Zhang Z, Xu H: Transcriptional regulation of APH-1A and improved gammasecretase cleavage of App and Notch by HIF-1 and hypoxia. FASEB J 2006, 20:1275?277. Wang Z, Yang D, Zhang X, Li T, Li J, Tang Y, Le W: Hypoxia-induced PubMed ID: down-regulation of neprilysin by histone modification in mouse primary cortical and hippocampal neurons. PLoS Just one 2011, six:e19229. Zhang X, Zhou K, Wang R, Cui J, Lipton SA, Liao FF, Xu H, Zhang YW: Hypoxia-inducible component 1alpha (HIF-1alpha)-mediated hypoxia improves BACE1 expression and beta-amyloid era. J Biol Chem 2007, 282:10873?0880. Marshall AJ, Rattray M, Vaughan PF: Chronic hypoxia within the human neuroblastoma SH-SY5Y triggers lessened expression on the putative -secretases, ADAM10 and TACE, with out altering their mRNA concentrations. Mind Res 2006, 1099:18?four. Webster NJ, Environmentally friendly KN, Peers C, Vaughan PF: Altered processing of amyloid precursor protein during the human neuroblastoma SH SY5Y by continual hypoxia. J Neurochem 2002, eighty three:1262?271. Iyer NV, Kotch LE, Agani F, Leung SW, Laughner E, Wenger RH, Gassmann M, Gearhart JD, Lawler AM, Aimee YY: Cellular and developmental control of O2 homeostasis by hypoxia-inducible element 1. Genes Dev 1998, 12:149?sixty two. Farris W, Sch z SG, Cirrito JR, Shankar GM, Sun X, George A, Leissring MA, Walsh DM, Qiu WQ, Holtzman DM: Loss of neprilysin purpose promotes amyloid plaque development and triggers cerebral amyloid angiopathy. Am J Pathol 2007, 171:241?51. Apelt J, Ach K, Schliebs R: Aging-related down-regulation of neprilysin, a putative -amyloid-degrading enzyme, in transgenic Tg2576 Alzheimer-like mouse mind is accompanied by an astroglial upregulation during the vicinity of -amyloid plaques. Neurosci Lett 2003, 339:183?86. Caccamo A, Oddo S, Sugarman MC, Akbari Y, LaFerla FM: Age-and region-dependent alterations in A-degrading enzymes: implications for A-induced conditions. Neurobiol Getting older 2005, 26:645?fifty four. Wang D-S, Lipton RB, Katz MJ, Davies P, Buschke H, Kuslansky G, Verghese J, Younkin SG, Eckman C, Dickson DW: Decreased neprilysin immunoreactivity in Alzheimer disease, but not in PubMed ID: pathological getting old. J Neuropathol Exp Neurol 2005, 64:378?85. Russo R, Borghi R, Markesbery W, Tabaton M, Piccini A: Neprylisin decreases uniformly in Alzheimer's disease and in standard aging. FEBS Lett 2005, 579:6027?030. Carpentier M, Robitaille Y, DesGroseillers L, Boileau G, Marcinkiewicz M: Declining expression of neprilysin in Alzheimer condition vasculature: probable involvement in cerebral amyloid angiopathy. J Neuropathol Exp Neurol 2002, sixty one:849?fifty six. Fisk L, Nalivaeva NN, Boyle JP, Peers CS, Turner AJ: Consequences of hypoxia and oxidative pressure on expression of neprilysin in human neuroblastoma cells and rat cortical neurones and astrocytes. Neurochem Res 2007, 32:1741?748. Nalivaevaa NN, Fisk L, Kochkina EG, Plesneva SA, Zhuravin IA, Babusikova E, Dobrota D, Turner AJ: Result of hypoxia/ischemia and hypoxic preconditioning/reperfusion on expression of some amyloid degrading enzymes. Ann N Edasalonexent Y Acad Sci 2004, 1035:21?three. Jaenisch R, Fowl A: Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003, 33:245?fifty four. Rodenhiser D, Mann M: Epigenetics and human ailment: translating essential biology into clinical programs. Can Med Assoc J 2006, 174:341?48.Liu and Le Translational Neurodegeneration 2014, three:seven http://www.translationalneurodegenera.